About the Authors

Ibrahim Musa Yola

Roles Conceptualization, Investigation, Writing – original draft

Affiliation Section of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, MA, United States of America

Albin Oh

Roles Writing – review & editing

Affiliation Department of Medicine, Boston Medical Center, Boston, MA, United States of America

Gary F. Mitchell

Roles Writing – review & editing

Affiliation Cardiovascular Engineering, Inc., Norwood, MA, United States of America

George O’Connor

Roles Writing – review & editing

Affiliation Department of Medicine, Pulmonary Center, Boston Medical Center, Boston University, Boston, MA, United States of America

Susan Cheng

Roles Writing – review & editing

Affiliation Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America

Ramachandran S. Vasan

Roles Writing – review & editing

Affiliations Section of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, MA, United States of America, National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, MA, United States of America, Department of Epidemiology, Boston University School of Public Health, Boston, MA, United States of America

Vanessa Xanthakis

Roles Investigation, Methodology, Supervision, Writing – review & editing

vanessax@bu.edu

Affiliations Section of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, MA, United States of America, National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, MA, United States of America, Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America

Competing Interests

Susan Cheng has received consulting fees from Zogenix for work unrelated to this manuscript. Gary F. Mitchell has the following disclosures: a) grants: NIH, Novartis (both significant); b) consulting: Novartis, Servier, Merck, Bayer (all significant); and c) ownership: Cardiovascular Engineering, Inc. (significant). These affiliations do not alter our adherence to PLOS ONE policies on sharing data and materials.