About the Authors

Eric D. Vidoni

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Supervision, Writing – original draft, Writing – review & editing

Affiliation University of Kansas Alzheimer’s Disease Center, Fairway, KS, United States of America

Jill K. Morris

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

Affiliation University of Kansas Alzheimer’s Disease Center, Fairway, KS, United States of America

Amber Watts

Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliation Department of Psychology, University of Kansas, Lawrence, KS, United States of America

Mark Perry

Roles Formal analysis, Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Radiology, University of Kansas Health System, Kansas City, KS, United States of America

Jon Clutton

Roles Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliation University of Kansas Alzheimer’s Disease Center, Fairway, KS, United States of America

Angela Van Sciver

Roles Investigation, Project administration, Supervision, Writing – review & editing

Affiliation University of Kansas Alzheimer’s Disease Center, Fairway, KS, United States of America

Ashwini S. Kamat

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation University of Kansas Alzheimer’s Disease Center, Fairway, KS, United States of America

Jonathan Mahnken

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

Affiliations University of Kansas Alzheimer’s Disease Center, Fairway, KS, United States of America, Department of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, KS, United States of America

Suzanne L. Hunt

Roles Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliations University of Kansas Alzheimer’s Disease Center, Fairway, KS, United States of America, Department of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, KS, United States of America

Ryan Townley

Roles Formal analysis, Writing – original draft, Writing – review & editing

Affiliation University of Kansas Alzheimer’s Disease Center, Fairway, KS, United States of America

Robyn Honea

Roles Conceptualization, Investigation, Methodology, Project administration, Software, Writing – original draft, Writing – review & editing

Affiliation University of Kansas Alzheimer’s Disease Center, Fairway, KS, United States of America

Ashley R. Shaw

Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliation University of Kansas Alzheimer’s Disease Center, Fairway, KS, United States of America

David K. Johnson

Roles Conceptualization, Investigation, Project administration, Writing – review & editing

Affiliation Department of Neurology, University of California–Davis, Sacramento, CA, United States of America

James Vacek

Roles Formal analysis, Investigation, Project administration, Writing – review & editing

Affiliation Department of Cardiovascular Medicine, University of Kansas Health System, Kansas City, KS, United States of America

Jeffrey M. Burns

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

jburns2@kumc.edu

Affiliation University of Kansas Alzheimer’s Disease Center, Fairway, KS, United States of America

Competing Interests

This work was supported by the National Institutes of Health R01 AG043962 (JMB); K99 AG050490 (JKM) and gifts from Frank and Evangeline Thompson (JMB), The Ann and Gary Dickinson Family Charitable Foundation, John and Marny Sherman, and Brad and Libby Bergman. Institutional infrastructure support for testing was provided in part by UL1 TR000001 (RJB) and P30 AG035982 (RHS JMB). Lilly Pharmaceuticals provided a grant to support F18-AV45 doses and partial scan costs (JMB). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. This does not alter our adherence to PLOS ONE policies on sharing data and materials.