About the Authors

Marie Sophie Friedrich

Roles Data curation, Validation, Writing – original draft

Affiliation Institute of Anesthesiology, University and University Hospital Zurich, Zurich, Switzerland

Jan-Dirk Studt

Roles Conceptualization, Data curation, Methodology, Validation, Writing – review & editing

Affiliation Division of Medical Oncology and Hematology, University and University Hospital Zurich, Zurich, Switzerland

Julia Braun

Roles Formal analysis, Methodology, Validation, Visualization, Writing – review & editing

Affiliation Departments of Epidemiology and Biostatistics, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland

Donat R. Spahn

Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Institute of Anesthesiology, University and University Hospital Zurich, Zurich, Switzerland

Alexander Kaserer

Roles Conceptualization, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

alexander.kaserer@usz.ch

Affiliation Institute of Anesthesiology, University and University Hospital Zurich, Zurich, Switzerland

Competing Interests

I have read the journal’s policy and the authors of this manuscript have the following competing interests: MSF and JB: none. AK: Received honoraria for lecturing from Bayer AG (Switzerland). JDS: advisory and lecture honoraria from Bayer (Switzerland), Shire/Takeda (Switzerland), BMS-Pfizer (Switzerland), Sanofi (Switzerland), Siemens Diagnostics (Switzerland). DRS: Dr. Spahn’s academic department is receiving grant support from the Swiss National Science Foundation, Berne, Switzerland, the Swiss Society of Anesthesiology and Reanimation (SGAR), Berne, Switzerland, the Swiss Foundation for Anesthesia Research, Zurich, Switzerland, Vifor SA, Villars-sur-Glâne, Switzerland. Dr. Spahn is co-chair of the ABC-Trauma Faculty, sponsored by unrestricted educational grants from Novo Nordisk Health Care AG, Zurich, Switzerland, CSL Behring GmbH, Marburg, Germany, LFB Biomédicaments, Courtaboeuf Cedex, France and Octapharma AG, Lachen, Switzerland. Dr. Spahn received honoraria / travel support for consulting or lecturing from: Danube University of Krems, Austria, US Department of Defense, Washington, USA, European Society of Anesthesiology, Brussels, BE, Korean Society for Patient Blood Management, Seoul, Korea, Korean Society of Anesthesiologists, Seoul, Korea, Network for the Advancement of Patient Blood Management, Haemostasis and Thrombosis, Paris, France, Baxter AG, Volketswil, Switzerland, Baxter S.p.A., Roma, Italy, Bayer AG, Zürich, Switzerland, Bayer Pharma AG, Berlin, Germany, B. Braun Melsungen AG, Melsungen, Germany, Boehringer Ingelheim GmbH, Basel, Switzerland, Bristol-Myers-Squibb, Rueil-Malmaison Cedex, France and Baar, Switzerland, CSL Behring GmbH, Hattersheim am Main, Germany and Berne, Switzerland, Celgene International II Sàrl, Couvet, Switzerland, Curacyte AG, Munich, Germany, Daiichi Sankyo AG, Thalwil, Switzerland, GlaxoSmithKline GmbH & Co. KG, Hamburg, Germany, Haemonetics, Braintree, MA, USA, Instrumentation Laboratory (Werfen), Bedford, MA, USA, LFB Biomédicaments, Courtaboeuf Cedex, France, Merck Sharp & Dohme, Kenilworth, New Jersey, USA, Octapharma AG, Lachen, Switzerland, Organon AG, Pfäffikon/SZ, Switzerland, PAION Deutschland GmbH, Aachen, Germany, Pharmacosmos A/S, Holbaek, Denmark, Photonics Healthcare B.V., Utrecht, Netherlands, Pierre Fabre Pharma, Alschwil, Switzerland, Roche Diagnostics International Ltd, Reinach, Switzerland, Roche Pharma AG, Reinach, Switzerland, Sarstedt AG & Co., Sevelen, Switzerland and Nümbrecht, Germany, Schering-Plough International, Inc., Kenilworth, New Jersey, USA, Tem International GmbH, Munich, Germany, Verum Diagnostica GmbH, Munich, Germany, Vifor Pharma, Munich, Germany, Vienna, Austria and Villars-sur-Glâne, Switzerland, Vifor (International) AG, St. Gallen, Switzerland, Zuellig Pharma Holdings, Singapore, Singapore. This does not alter our adherence to PLOS ONE policies on sharing data and materials.