About the Authors

Jun Shoji

Contributed equally to this work with: Jun Shoji, Noriko Inada, Akiko Tomioka, Satoru Yamagami

Roles Investigation, Methodology, Writing – original draft

Affiliation Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Tokyo, Japan

Noriko Inada

Contributed equally to this work with: Jun Shoji, Noriko Inada, Akiko Tomioka, Satoru Yamagami

Roles Investigation

Affiliation Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Tokyo, Japan

Akiko Tomioka

Contributed equally to this work with: Jun Shoji, Noriko Inada, Akiko Tomioka, Satoru Yamagami

Roles Investigation

Affiliation Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Tokyo, Japan

Satoru Yamagami

Contributed equally to this work with: Jun Shoji, Noriko Inada, Akiko Tomioka, Satoru Yamagami

Roles Writing – review & editing

satoru.yamagami@nihon-u.ac.jp

Affiliation Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Tokyo, Japan

Competing Interests

Financial support for this research was received from the Otsuka Pharmaceutical Co., Ltd., Japan. I have read the journal's policy and the authors of this manuscript have the following competing interests: J.S. received personal fees from Santen Pharmaceutical Co. Ltd., Senju Pharmaceutical Co. Ltd., Alcon Pharmaeuticals, outside the submitted work. Y.S., N.I., and A.T. declare that they have no conflict of interest. This does not alter our adherence to PLOS ONE policies on sharing data and materials.