About the Authors

Ruiying Hu

Roles Formal analysis, Methodology, Software, Supervision, Writing – review & editing

Affiliation Department of Cell and Developmental Biology, The Program of Developmental Biology and the Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, United States of America

Xiaodong Zhu

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – review & editing

Current address: Department of Medicine and Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, United States of America

Affiliation Department of Cell and Developmental Biology, The Program of Developmental Biology and the Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, United States of America

Mingyang Yuan

Roles Formal analysis, Investigation, Methodology, Software, Writing – review & editing

Affiliation Department of Cell and Developmental Biology, The Program of Developmental Biology and the Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, United States of America

Kung-Hsien Ho

Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – review & editing

Affiliation Department of Cell and Developmental Biology, The Program of Developmental Biology and the Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, United States of America

Irina Kaverina

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

Guoqiang.Gu@vanderbilt.edu (GG); Irina.Kaverina@vanderbilt.edu (IK)

Affiliation Department of Cell and Developmental Biology, The Program of Developmental Biology and the Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, United States of America

Guoqiang Gu

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

Guoqiang.Gu@vanderbilt.edu (GG); Irina.Kaverina@vanderbilt.edu (IK)

Affiliation Department of Cell and Developmental Biology, The Program of Developmental Biology and the Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, United States of America

Competing Interests

One of the co-authors (Dr. Ho) has received a fellowship from Eli Lilly and Company. However, this does not alter our adherence to PLOS ONE policies on sharing data and materials.