About the Authors

Qingqin S. Li

Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Resources, Visualization, Writing – original draft, Writing – review & editing

qli2@its.jnj.com

Affiliation Janssen Research & Development, LLC, Titusville, NJ, United States of America

Chao Tian

Roles Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – review & editing

Affiliation 23andMe, Inc., Mountain View, CA, United States of America

The 23andMe Research Team

Membership of the The 23andMe Research Team is listed in the Acknowledgments.

Affiliation 23andMe, Inc., Mountain View, CA, United States of America

David Hinds

Roles Investigation, Methodology, Supervision, Writing – review & editing

Affiliation 23andMe, Inc., Mountain View, CA, United States of America

Guy R. Seabrook

Roles Funding acquisition, Writing – review & editing

Affiliation Johnson & Johnson Innovation, South San Francisco, CA, United States of America

Competing Interests

QSL and GRS are employees of Janssen Research & Development, LLC and may own stock/stock options in the company. CT, DAH and members of the 23andMe Research Team are or have been employed by 23andMe, Inc. and may own stock/stock options in the company. Due to the user agreement (available at https://www.23andme.com/about/tos/) where it states “Genetic and/or Self-Reported Information. Disclosure of individual-level Genetic Information and/or Self-Reported Information to third parties for Research purposes will not occur without explicit consent.”, the individual level cannot be made directly available to scientific community but have to be accessed indirectly via 23andMe. A file containing full summary association statistics is available in the Supplemental Material.