About the Authors

Bo Liu

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

b.liu7@herts.ac.uk

Affiliation Department of Clinical, Pharmaceutical and Biological Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, Hertfordshire, United Kingdom

Keith Davies

Contributed equally to this work with: Keith Davies, Avice Hall

Roles Methodology, Supervision, Writing – review & editing

Affiliations Department of Clinical, Pharmaceutical and Biological Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, Hertfordshire, United Kingdom, Division of Biotechnology and Plant Health, Norwegian Institute of Bioeconomy Research, Ås, Norway

Avice Hall

Contributed equally to this work with: Keith Davies, Avice Hall

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

Affiliation Department of Clinical, Pharmaceutical and Biological Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, Hertfordshire, United Kingdom

Competing Interests

The authors have read the journal's policy and have the following competing interests: This study was partially (no more than 15 percent of the overall funding) funded by Orion Future Technology Ltd (http://orionft.com). The funder does not serve on the editorial board of this submission, is not on a committee that may benefit from publication of the paper. The product used is not patented and is for sale. It has not been marketed into this sector. This does not alter our adherence to PLOS ONE policies on sharing data and materials.