Maximizing cohesion and separation for detecting protein functional modules in protein-protein interaction networks

Kuo-Ching Ying; Shih-Wei Lin

doi:10.1371/journal.pone.0240628

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Open Access

Peer-reviewed

Research Article

Maximizing cohesion and separation for detecting protein functional modules in protein-protein interaction networks

Kuo-Ching Ying,

Roles Investigation, Methodology, Writing – original draft

Affiliation Department of Industrial Engineering and Management, National Taipei University of Technology, Taipei, Taiwan
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Shih-Wei Lin

Roles Software, Supervision, Writing – review & editing

* E-mail: swlin@mail.cgu.edu.tw

Affiliations Department of Information Management, Chang Gung University, Taoyuan, Taiwan, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan, Ming Chi University of Technology, Taipei, Taiwan

http://orcid.org/0000-0003-1343-0838

⨯

Maximizing cohesion and separation for detecting protein functional modules in protein-protein interaction networks

Kuo-Ching Ying,
Shih-Wei Lin

Published: October 13, 2020
https://doi.org/10.1371/journal.pone.0240628

About the Authors

Kuo-Ching Ying

Roles Investigation, Methodology, Writing – original draft

Affiliation Department of Industrial Engineering and Management, National Taipei University of Technology, Taipei, Taiwan

Shih-Wei Lin

Roles Software, Supervision, Writing – review & editing

* E-mail: swlin@mail.cgu.edu.tw

Affiliations Department of Information Management, Chang Gung University, Taoyuan, Taiwan, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan, Ming Chi University of Technology, Taipei, Taiwan

http://orcid.org/0000-0003-1343-0838

Competing Interests

The authors have declared that no competing interest exist.

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Algorithms
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Gene ontologies
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Optimization
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Protein interaction networks
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Hierarchical clustering
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Network analysis
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Protein interactions
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Protein complexes
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