About the Authors

Sang Hun Lee

Contributed equally to this work with: Sang Hun Lee, David Lutz

Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Writing – original draft, Writing – review & editing

slee82@bwh.harvard.edu

Affiliation Department of Neurology, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

David Lutz

Contributed equally to this work with: Sang Hun Lee, David Lutz

Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Current address: Department for Neuroanatomy and Molecular Brain Research, Ruhr-University Bochum, Bochum, Germany

Affiliation Institute for Structural Neurobiology, Center for Molecular Neurobiology Hamburg (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Dagmar Drexler

Roles Resources

Current address: Center for Diagnostics, Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Affiliation Institute for Structural Neurobiology, Center for Molecular Neurobiology Hamburg (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Michael Frotscher

† Deceased.

Roles Supervision

Affiliation Institute for Structural Neurobiology, Center for Molecular Neurobiology Hamburg (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Jie Shen

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliations Department of Neurology, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Program in Neuroscience, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

J.S. is a member of the Board of Directors and has a financial interest in iNeuro Therapeutics, and J.S. also has a financial interest in Apres Therapeutics. Both companies develop therapies for Alzheimer’s disease. J.S.’s interests were reviewed and are managed by BWH and Partners HealthCare in accordance with their conflict of interest policies.