Modelling bioactivities of combinations of whole extracts of edibles with a simplified theoretical framework reveals the statistical role of molecular diversity and system complexity in their mode of action and their nearly certain safety

Pascal Mayer

doi:10.1371/journal.pone.0239841

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Open Access

Peer-reviewed

Research Article

Modelling bioactivities of combinations of whole extracts of edibles with a simplified theoretical framework reveals the statistical role of molecular diversity and system complexity in their mode of action and their nearly certain safety

Pascal Mayer

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: pascal.mayer@alphanosos.com

Affiliation Alphanosos, Riom, France

http://orcid.org/0000-0003-3348-9036

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Modelling bioactivities of combinations of whole extracts of edibles with a simplified theoretical framework reveals the statistical role of molecular diversity and system complexity in their mode of action and their nearly certain safety

Pascal Mayer

Published: September 28, 2020
https://doi.org/10.1371/journal.pone.0239841

About the Authors

Pascal Mayer

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: pascal.mayer@alphanosos.com

Affiliation Alphanosos, Riom, France

http://orcid.org/0000-0003-3348-9036

Competing Interests

This work was financially supported by Alphanosos. The author is an employee, corporate representative, manager, and shareholder of Alphanosos. This does not alter the author’s adherence to PLOS ONE policies on sharing data and materials. The following patents, marketed products, or products in development are related to this work: - Patent family, applied for in 71 countries, including WO2018083115 and US2019255136 - Ediceutical based antibiotics and anti-cancer actives (preclinical research) - Cosmetic ingredients: Synherbs®4.5, Synherbs®5.1, Synherbs®5.2 - Veterinary hygiene products Effiskin®, PhytoPyo,®, CaniPerfect® - Cosmetic product Mokaskin® - Alternatives to antibiotics for agriculture (preregistration research)

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Nutrients
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Homeostasis
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Food poisoning
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Adverse reactions
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Toxicity
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Microbiome
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Toxins
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Cancer treatment
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