About the Authors

Daijo Inaguma

Contributed equally to this work with: Daijo Inaguma, Akimitsu Kitagawa, Ryosuke Yanagiya, Akira Koseki, Toshiya Iwamori

Roles Conceptualization, Writing – original draft, Writing – review & editing

daijo@fujita-hu.ac.jp

Affiliation Department of Internal Medicine, Fujita Health University Bantane Hospital–Nagoya, Japan

Akimitsu Kitagawa

Contributed equally to this work with: Daijo Inaguma, Akimitsu Kitagawa, Ryosuke Yanagiya, Akira Koseki, Toshiya Iwamori

Roles Data curation, Writing – original draft

Affiliation Department of Internal Medicine, Fujita Health University Bantane Hospital–Nagoya, Japan

Ryosuke Yanagiya

Contributed equally to this work with: Daijo Inaguma, Akimitsu Kitagawa, Ryosuke Yanagiya, Akira Koseki, Toshiya Iwamori

Roles Project administration

Affiliation Division of Medical Information Systems, Fujita Health University School of Medicine–Toyoake, Japan

Akira Koseki

Contributed equally to this work with: Daijo Inaguma, Akimitsu Kitagawa, Ryosuke Yanagiya, Akira Koseki, Toshiya Iwamori

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft

Affiliation IBM Research—Tokyo, Japan

Toshiya Iwamori

Contributed equally to this work with: Daijo Inaguma, Akimitsu Kitagawa, Ryosuke Yanagiya, Akira Koseki, Toshiya Iwamori

Roles Data curation, Formal analysis, Methodology

Affiliation IBM Research—Tokyo, Japan

Michiharu Kudo

Roles Supervision

‡ These authors also contributed equally to this work.

Affiliation IBM Research—Tokyo, Japan

Yukio Yuzawa

Roles Supervision

‡ These authors also contributed equally to this work.

Affiliation Department of Nephrology, Fujita Health University School of Medicine–Toyoake, Japan

Competing Interests

DI received lecture fees from Ono Pharmaceutical Co., Ltd. and Kyowa Hakko Kirin Co. YY received research support grants from Otsuka Pharmaceutical Co., Ltd., Kyowa Hakko Kirin Co., Ltd., and Chugai Pharmaceutical Co., Ltd. IBM Research provided support for this study in the form of salaries for AK, TI and MK. There are no patents, products in development or marketed products associated with this research to declare. This does not alter our adherence to PLOS ONE policies on sharing data and materials.