About the Authors

Risa Mitsumori

Roles Formal analysis

Affiliation Medical Genome Center, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

Kazuya Sakaguchi

Roles Formal analysis, Software

Current address: Axcelead Drug Discovery Partners, Inc., Fujisawa, Kanagwa, Japan

Affiliation Department of Regenerative Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

Daichi Shigemizu

Roles Formal analysis, Writing – review & editing

Affiliation Medical Genome Center, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

Taiki Mori

Roles Formal analysis, Writing – review & editing

Current address: Department of Oral Microbiology, Asahi University School of Dentistry, Mizuho, Gifu, Japan

Affiliation Medical Genome Center, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

Shintaro Akiyama

Roles Formal analysis, Writing – review & editing

Affiliation Medical Genome Center, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

Kouichi Ozaki

Roles Formal analysis, Writing – review & editing

Affiliation Medical Genome Center, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

Shumpei Niida

Roles Resources

Affiliation Medical Genome Center, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

Nobuyoshi Shimoda

Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft

shimoda@ncgg.go.jp

Affiliation Department of Regenerative Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

Competing Interests

The authors have declared that no competing interests exist. K.S. is affiliated with Axcelead Drug Discovery Partners, Inc., Fujisawa, Kanagawa, Japan. This does not alter our adherence to PLOS ONE policies on sharing data and materials.