About the Authors

Makiko Ogawa

Contributed equally to this work with: Makiko Ogawa, Yukako Shintani-Domoto

Roles Investigation, Resources, Writing – original draft

Affiliations Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

Yukako Shintani-Domoto

Contributed equally to this work with: Makiko Ogawa, Yukako Shintani-Domoto

Roles Conceptualization, Funding acquisition, Investigation, Resources, Writing – review & editing

Affiliation Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Yoshiki Nagashima

Roles Data curation, Methodology, Resources, Writing – review & editing

Affiliations Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Thermo Fisher Scientific K.K., Yokohama, Kanagawa, Japan

Koji L. Ode

Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft

Affiliation Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Aya Sato

Roles Investigation, Methodology

Affiliation Laboratory for Cell-Free Protein Synthesis, RIKEN Center for Biosystems Dynamics Research, Suita, Osaka, Japan

Yoshihiro Shimizu

Roles Methodology, Supervision, Writing – review & editing

Affiliation Laboratory for Cell-Free Protein Synthesis, RIKEN Center for Biosystems Dynamics Research, Suita, Osaka, Japan

Kenichi Ohashi

Roles Conceptualization, Writing – review & editing

Affiliation Department of Pathology, Graduate School of Medicine, Yokohama City University, Yokohama, Japan

Michael H. A. Roehrl

Roles Supervision, Writing – review & editing

Affiliations Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

Tetsuo Ushiku

Roles Supervision, Writing – review & editing

Affiliation Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Hiroki R. Ueda

Roles Conceptualization, Supervision, Writing – review & editing

Affiliations Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Laboratory for Synthetic Biology, RIKEN Center for Biosystems Dynamics Research, Suita, Osaka, Japan

Masashi Fukayama

Roles Conceptualization, Project administration, Supervision, Writing – review & editing

mfukayama-tky@umin.org

Affiliations Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Asahi TelePathology Center, Asahi General Hospital, Asahi-City, Chiba, Japan

Competing Interests

H.R.U conducted a collaborative research project with Thermo Fisher Scientific Inc. Y.N. is an employee of Thermo Fisher Scientific, Inc. The company provided support in the form of salary for Y.N., and technical advice on the setup of mass spectrometers. M.H.R. is a member of the Scientific Advisory Boards of Proscia, Trans-Hit, and Universal DX. There are no patents, products in development or marketed products associated with this research to declare. This does not alter our adherence to PLOS ONE policies on sharing data and materials.