About the Authors

M. Iqbal Choudhary

Contributed equally to this work with: M. Iqbal Choudhary, Muniza Shaikh, Atia- tul-Wahab, Atta- ur-Rahman

Roles Conceptualization, Supervision, Writing – review & editing

iqbal.choudhary@iccs.edu (MIC); shaikhmuniza2016@gmail.com (MS); atia.tulwahab@iccs.edu (ATW)

Affiliations Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan, H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Muniza Shaikh

Contributed equally to this work with: M. Iqbal Choudhary, Muniza Shaikh, Atia- tul-Wahab, Atta- ur-Rahman

Roles Investigation, Methodology, Software, Writing – original draft

iqbal.choudhary@iccs.edu (MIC); shaikhmuniza2016@gmail.com (MS); atia.tulwahab@iccs.edu (ATW)

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Atia- tul-Wahab

Contributed equally to this work with: M. Iqbal Choudhary, Muniza Shaikh, Atia- tul-Wahab, Atta- ur-Rahman

Roles Conceptualization, Supervision, Writing – review & editing

iqbal.choudhary@iccs.edu (MIC); shaikhmuniza2016@gmail.com (MS); atia.tulwahab@iccs.edu (ATW)

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Atta- ur-Rahman

Contributed equally to this work with: M. Iqbal Choudhary, Muniza Shaikh, Atia- tul-Wahab, Atta- ur-Rahman

Roles Conceptualization, Formal analysis, Writing – review & editing

Affiliations Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan, H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Competing Interests

The study has financial support of the Searle Company, Pakistan through a research project funding. This does not alter our adherence to PLOS ONE policies on sharing data and materials.