About the Authors

Khanutsanan Woranam

Roles Investigation, Methodology, Writing – original draft

Affiliation Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen, Thailand

Gulsiri Senawong

Roles Data curation, Resources, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen, Thailand

Suppawit Utaiwat

Roles Investigation

Affiliation Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen, Thailand

Sirinda Yunchalard

Roles Supervision, Writing – review & editing

Affiliation Department of Biotechnology, Faculty of Technology, Khon Kaen University, Khon Kaen, Thailand

Jintana Sattayasai

Roles Supervision, Writing – review & editing

Affiliation Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

Thanaset Senawong

Roles Conceptualization, Funding acquisition, Project administration, Resources, Validation, Writing – original draft, Writing – review & editing

sthanaset@kku.ac.th

Affiliations Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen, Thailand, Natural Product Research Unit, Faculty of Science, Khon Kaen University, Khon Kaen, Thailand

Competing Interests

I would like to undertake that all of authors have no relation with the Prolac (Thailand) Co., Ltd., who is a co-funder with Thailand Research Fund (TRF) on the Research and Researcher for Industry (RRi) project. The company provided 60,000 baht in cash and the HCFP samples (product Lot no. 14/5/2015), while the TRF provided a Ph.D. scholarship and major funding source for the project. This does not alter our adherence to PLOS ONE policies on sharing data and materials.