About the Authors

Carlos Kramm

Roles Investigation, Methodology, Writing – review & editing

Affiliations Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States of America, Universidad de Los Andes, Facultad de Medicina, Las Condes, Santiago, Chile

Ruben Gomez-Gutierrez

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliations Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States of America, Department of Cell Biology, University of Malaga, Malaga, Spain

Claudio Soto

Roles Resources

Affiliation Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States of America

Glenn Telling

Roles Resources

Affiliation Prion Research Center, Colorado State University, Fort Collins, CO, United States of America

Tracy Nichols

Roles Conceptualization, Investigation, Resources, Writing – review & editing

Affiliation Veterinary Services, APHIS, United States Department of Agriculture, Fort Collins, CO, United States of America

Rodrigo Morales

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft

Rodrigo.MoralesLoyola@uth.tmc.edu

Affiliations Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States of America, CIBQA, Universidad Bernardo OHiggins. Santiago, Chile

Competing Interests

Dr. Morales and Dr. Soto are listed as inventors in one patent related to the PMCA technology (“Methods for estimating prion concentration in fluids and tissue by quantitative PMCA” US20110311997A1). Dr. Soto is inventor on several patents related to the PMCA technology and is currently Founder, Chief Scientific Officer and Vice-President of Amprion Inc, a biotech company focusing on the commercial utilization of PMCA for diagnosis of various neurodegenerative diseases. This does not alter our adherence to PLOS ONE policies on sharing data and materials.