http://orcid.org/0000-0001-6413-8680
About the Authors
- George W. Cook
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Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Sentry Genomics, Baton Rouge, LA, United States of America
- Michael G. Benton
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Roles Formal analysis, Writing – original draft, Writing – review & editing
Affiliation Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA, United States of America
- Wallace Akerley
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Roles Investigation, Writing – review & editing
Affiliation Huntsman Cancer Institute, University of Utah School of Medicine, Department of Oncological Sciences, Salt Lake City, UT, United States of America
- George F. Mayhew
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Roles Methodology
Affiliation Roche Sequencing Solutions, Madison, WI, United States of America
- Cynthia Moehlenkamp
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Roles Methodology
Affiliation Roche Sequencing Solutions, Madison, WI, United States of America
- Denise Raterman
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Roles Methodology, Resources, Supervision, Writing – original draft
Affiliation Roche Sequencing Solutions, Madison, WI, United States of America
- Daniel L. Burgess
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Roles Methodology, Resources, Supervision
Affiliation Roche Sequencing Solutions, Madison, WI, United States of America
- William J. Rowell
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Roles Data curation, Methodology, Software, Writing – review & editing
Affiliation Pacific Biosciences, Menlo Park, CA, United States of America
- Christine Lambert
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Roles Methodology
Affiliation Pacific Biosciences, Menlo Park, CA, United States of America
- Kevin Eng
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Roles Methodology
Affiliation Pacific Biosciences, Menlo Park, CA, United States of America
- Jenny Gu
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Roles Resources, Supervision, Writing – review & editing
Affiliation Pacific Biosciences, Menlo Park, CA, United States of America
- Primo Baybayan
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Roles Methodology
Affiliation Pacific Biosciences, Menlo Park, CA, United States of America
- John T. Fussell
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Roles Formal analysis, Software, Validation
Affiliation Sentry Genomics, Baton Rouge, LA, United States of America
- Heath D. Herbold
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Roles Data curation, Formal analysis, Visualization
Affiliation Sentry Genomics, Baton Rouge, LA, United States of America
- John M. O’Shea
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Roles Methodology, Resources
Affiliation Huntsman Cancer Institute, Biorepository Molecular Pathology, Salt Lake City, UT, United States of America
- Thomas K. Varghese
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Roles Investigation
Affiliation Huntsman Cancer Institute, University of Utah School of Medicine, Department of Surgery, Division of Thoracic Surgery, Salt Lake City, UT, United States of America
- Lyska L. Emerson
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Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing
* E-mail: lyska.emerson@hsc.utah.edu
Affiliation Huntsman Cancer Institute, University of Utah School of Medicine, Department of Pathology, Salt Lake City, UT, United States of America
Competing Interests
Lion Elastomers and Nouryon Polymer Chemicals are in no way attached to any consultancy, patents, products in development or marketed products etc. related to this manuscript. George W. Cook is a co-owner and co-founder of Sentry Genomics, LLC. George holds two patents related to the Alu-element based genome instability model published previously in PLOS ONE (https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065188). Patent Title: Clinical use of an Alu element based bioinformatics methodology for the detection and treatment of cancer, patent no’s 9,932,640 and 10,242,154. All Pacific Biosciences employees [WJR, CL, KE, JG, PB] own stocks and shares in Pacific Biosciences. Roche Sequencing Solutions employees [GFM, CM, DR, DLB] do not own company stock or shares. None of the aforementioned authors affiliated with these commercial entities have any financial or non-financial competing interest with PLOS ONE, and the contribution of these authors to this manuscript does not alter our adherence to all PLOS ONE policies on sharing data and materials.