Formation of a structurally-stable conformation by the intrinsically disordered MYC:TRRAP complex

Edmond J. Feris; John W. Hinds; Michael D. Cole

doi:10.1371/journal.pone.0225784

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Open Access

Peer-reviewed

Research Article

Formation of a structurally-stable conformation by the intrinsically disordered MYC:TRRAP complex

Edmond J. Feris,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

Affiliations Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States of America, Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States of America

http://orcid.org/0000-0001-9649-2844

⨯
John W. Hinds,

Roles Investigation, Methodology

Affiliations Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States of America, Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States of America
⨯
Michael D. Cole

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: Michael.D.Cole@dartmouth.edu

Affiliations Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States of America, Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States of America

http://orcid.org/0000-0002-3421-5451

⨯

Formation of a structurally-stable conformation by the intrinsically disordered MYC:TRRAP complex

Edmond J. Feris,
John W. Hinds,
Michael D. Cole

Published: December 2, 2019
https://doi.org/10.1371/journal.pone.0225784

About the Authors

Edmond J. Feris

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

Affiliations Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States of America, Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States of America

http://orcid.org/0000-0001-9649-2844

John W. Hinds

Roles Investigation, Methodology

Michael D. Cole

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: Michael.D.Cole@dartmouth.edu

http://orcid.org/0000-0002-3421-5451

Competing Interests

The authors have declared that no competing interests exist.

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Cancers and neoplasms
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Protein structure
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Protein structure prediction
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Drug interactions
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Carcinogenesis
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Protein interactions
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Transcription factors
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Protein domains
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