About the Authors

Qin Huang

Roles Conceptualization, Investigation, Methodology, Writing – review & editing

Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America

Ken Y. Chan

Roles Investigation, Methodology, Writing – review & editing

Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America

Isabelle G. Tobey

Roles Investigation, Writing – review & editing

Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America

Yujia Alina Chan

Roles Conceptualization, Writing – original draft

Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America

Tim Poterba

Roles Investigation, Software, Writing – review & editing

Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America

Christine L. Boutros

Roles Investigation

Affiliation Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, United States of America

Alejandro B. Balazs

Roles Investigation, Resources

Affiliation Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, United States of America

Richard Daneman

Roles Resources, Writing – review & editing

Affiliations Departments of Neurosciences and Pharmacology, University of California, San Diego, La Jolla, CA, United States of America, Department of Pharmacology, University of California, San Diego, La Jolla, CA, United States of America

Jonathan M. Bloom

Roles Investigation, Methodology, Writing – review & editing

Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America

Cotton Seed

Roles Investigation, Methodology, Writing – review & editing

Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America

Benjamin E. Deverman

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

bdeverma@broadinstitute.org

Affiliation Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America

Competing Interests

B.D. and K.C. are inventors on patents related to the AAV-PHP.B vectors filed by the California Institute of Technology; a provisional patent application related to this work controlled by the Broad Institute has been filed; B.D. is a consultant for Voyager Therapeutics and a member of the Scientific Advisory Board for Tevard Therapeutics. All other authors declare no competing interests. This does not alter our adherence to PLOS ONE policies on sharing data and materials.