About the Authors

Andrea De Gaetano

Roles Conceptualization, Methodology, Software, Writing – original draft, Writing – review & editing

andrea.degaetano@biomatematica.it

Affiliation CNR-IASI BioMatLab (Italian National Research Council - Institute of Analysis, Systems and Computer Science - Biomathematics Laboratory), Rome, Italy

Thomas Andrew Hardy

Roles Conceptualization, Investigation, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliation Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America

Competing Interests

The authors have declared that no competing interests exist. In particular, although Thomas Hardy is an employee of Ely Lilly & Company, USA, this does not alter our adherence to PLOS ONE policies on sharing data and materials.