About the Authors

Adam M. Corrigan

Roles Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

adam.corrigan@astrazeneca.com

Affiliation Discovery Sciences, R&D, AstraZeneca, Cambridge, United Kingdom

Johan Karlsson

Roles Conceptualization, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliation Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden

Jan Wildenhain

Roles Writing – original draft, Writing – review & editing

Current address: Syngenta, Jealott’s Hill Research Centre, Bracknell, United Kingdom

Affiliation Discovery Sciences, R&D, AstraZeneca, Cambridge, United Kingdom

Laurent Knerr

Roles Methodology

Affiliation Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

Maria Ölwegård-Halvarsson

Roles Investigation, Methodology

Affiliation Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

Maria Karlsson

Roles Investigation, Methodology

Affiliation Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

Svenja Lünse

Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden

Yinhai Wang

Roles Methodology, Software, Writing – review & editing

Affiliation Discovery Sciences, R&D, AstraZeneca, Cambridge, United Kingdom

Competing Interests

The funding for this research was provided by AstraZeneca. All authors are or were employees of AstraZeneca. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.