Telomere length and its correlation with gene mutations in chronic lymphocytic leukemia in a Korean population

Da Young Song; Jung-Ah Kim; Dajeong Jeong; Jiwon Yun; Sung-Min Kim; Kyumin Lim; Si Nae Park; Kyongok Im; Sungbin Choi; Sung-Soo Yoon; Dong Soon Lee

doi:10.1371/journal.pone.0220177

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Open Access

Peer-reviewed

Research Article

Telomere length and its correlation with gene mutations in chronic lymphocytic leukemia in a Korean population

Da Young Song,

Roles Formal analysis, Validation, Visualization, Writing – original draft

Affiliation Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea

http://orcid.org/0000-0003-2836-8862

⨯
Jung-Ah Kim,

Roles Data curation, Formal analysis, Investigation

Affiliations Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea, Department of Laboratory Medicine, Chung-Ang University Hospital, Seoul, Korea
⨯
Dajeong Jeong,

Roles Formal analysis

Affiliation Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea
⨯
Jiwon Yun,

Roles Formal analysis

Affiliation Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea
⨯
Sung-Min Kim,

Roles Investigation

Affiliation Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
⨯
Kyumin Lim,

Roles Investigation

Affiliation Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
⨯
Si Nae Park,

Roles Investigation

Affiliation Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
⨯
Kyongok Im,

Roles Investigation

Affiliation Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
⨯
Sungbin Choi,

Roles Investigation

Affiliation University of British Columbia, Vancouver, Canada
⨯
Sung-Soo Yoon,

Roles Data curation

Affiliations Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
⨯
Dong Soon Lee

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: soonlee@snu.ac.kr

Affiliations Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
⨯

Telomere length and its correlation with gene mutations in chronic lymphocytic leukemia in a Korean population

Da Young Song,
Jung-Ah Kim,
Dajeong Jeong,
Jiwon Yun,
Sung-Min Kim,
Kyumin Lim,
Si Nae Park,
Kyongok Im,
Sungbin Choi,
Sung-Soo Yoon

Published: July 23, 2019
https://doi.org/10.1371/journal.pone.0220177

About the Authors

Da Young Song

Roles Formal analysis, Validation, Visualization, Writing – original draft

Affiliation Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea

http://orcid.org/0000-0003-2836-8862

Jung-Ah Kim

Roles Data curation, Formal analysis, Investigation

Affiliations Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea, Department of Laboratory Medicine, Chung-Ang University Hospital, Seoul, Korea

Dajeong Jeong

Roles Formal analysis

Affiliation Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea

Jiwon Yun

Roles Formal analysis

Affiliation Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea

Sung-Min Kim

Roles Investigation

Affiliation Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Kyumin Lim

Roles Investigation

Affiliation Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Si Nae Park

Roles Investigation

Affiliation Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Kyongok Im

Roles Investigation

Affiliation Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Sungbin Choi

Roles Investigation

Affiliation University of British Columbia, Vancouver, Canada

Sung-Soo Yoon

Roles Data curation

Affiliations Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Dong Soon Lee

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: soonlee@snu.ac.kr

Affiliations Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Competing Interests

The authors have declared that no competing interests exist.

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Telomere length
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Karyotypes
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Chronic lymphoblastic leukemia
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Mutation
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Telomeres
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Cytogenetics
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Fluorescent in situ hybridization
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Lymphocytes
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