About the Authors

J. P. M. Blair

Roles Formal analysis, Investigation, Methodology, Writing – original draft

jbl@nordicbio.com

Affiliations ProScion, Herlev, Denmark, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark

C. Bager

Roles Conceptualization, Investigation, Supervision, Writing – review & editing

Affiliation ProScion, Herlev, Denmark

A. Platt

Roles Data curation, Investigation, Writing – review & editing

Affiliation Target & Translational Science, Respiratory, Inflammation and Autoimmunity (RIA), IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden

M. Karsdal

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Rheumatology, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark

A. -C. Bay-Jensen

Roles Conceptualization, Data curation, Supervision, Writing – original draft

Affiliation Rheumatology, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark

Competing Interests

ACBJ and MK are full-time employees and shareholders in Nordic Bioscience, a privately owned biotech company involved in development of biomarkers. The research in the manuscript have neither been restricted or censored by any board at Nordic Bioscience. AP is full-time employee and shareholder at Astra Zeneca. The manuscript, however not the research process, was reviewed and approved by the publication board at Astra Zeneca. The manuscript has not been censored by any bodies. This does not alter our adherence to PLOS ONE policies on sharing data and materials.