About the Authors

Delphine Bachelet

Contributed equally to this work with: Delphine Bachelet, Thilo Albert

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft

Affiliation CESP, INSERM UMR 1018, Faculty of Medicine, Paris-Sud University, UVSQ, Paris-Saclay University, Villejuif, France

Thilo Albert

Contributed equally to this work with: Delphine Bachelet, Thilo Albert

Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Writing – review & editing

Affiliation Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany

Cyprien Mbogning

Roles Formal analysis, Methodology, Writing – review & editing

Affiliation CESP, INSERM UMR 1018, Faculty of Medicine, Paris-Sud University, UVSQ, Paris-Saclay University, Villejuif, France

Signe Hässler

Roles Conceptualization, Data curation, Formal analysis, Writing – review & editing

Affiliation CESP, INSERM UMR 1018, Faculty of Medicine, Paris-Sud University, UVSQ, Paris-Saclay University, Villejuif, France

Yuan Zhang

Roles Data curation, Formal analysis, Writing – review & editing

Affiliation CESP, INSERM UMR 1018, Faculty of Medicine, Paris-Sud University, UVSQ, Paris-Saclay University, Villejuif, France

Stephan Schultze-Strasser

Roles Conceptualization, Data curation, Writing – review & editing

Affiliation University Hospital Frankfurt, Goethe University, Department of Pediatrics, Molecular Haemostasis and Immunodeficiency, Frankfurt am Main, Germany

Yohann Repessé

Roles Data curation, Methodology, Writing – review & editing

Affiliation CHU Caen, Hématologie Biologique, Caen, Caen, France

Julie Rayes

Roles Data curation, Writing – review & editing

Affiliation Sorbonne Universités, UPMC Univ Paris 06, INSERM, Université Paris Descartes, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France

Anna Pavlova

Roles Formal analysis, Writing – review & editing

Affiliation Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany

Behnaz Pezeshkpoor

Roles Formal analysis, Writing – review & editing

Affiliation Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany

Kerstin Liphardt

Roles Formal analysis, Writing – review & editing

Affiliation Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany

Julie E. Davidson

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

Affiliation GlaxoSmithKline, Uxbridge, Middlesex, United Kingdom

Agnès Hincelin-Méry

Roles Supervision, Writing – review & editing

Affiliation Sanofi, Chilly-Mazarin, France

Pierre Dönnes

Roles Conceptualization, Data curation, Methodology, Software, Writing – review & editing

Affiliation SciCross AB, Skövde, Sweden

Sébastien Lacroix-Desmazes

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

Affiliation Sorbonne Universités, UPMC Univ Paris 06, INSERM, Université Paris Descartes, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France

Christoph Königs

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation University Hospital Frankfurt, Goethe University, Department of Pediatrics, Molecular Haemostasis and Immunodeficiency, Frankfurt am Main, Germany

Johannes Oldenburg

Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

Affiliation Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany

Philippe Broët

Roles Conceptualization, Methodology, Supervision, Writing – original draft

philippe.broet@inserm.fr

Affiliations CESP, INSERM UMR 1018, Faculty of Medicine, Paris-Sud University, UVSQ, Paris-Saclay University, Villejuif, France, AP-HP, Paris-Sud University Hospitals, Villejuif, France

on behalf of the ABIRISK consortium

Membership of the ABIRISK Consortium is provided in the Acknowledgments section.

Competing Interests

D. Bachelet, T. Albert, C. Mbogning, S. H¨assler, Y. Zhang, S. Schultze-Strasser, Y Repesse, J. Rayes, A. Pavlova, B. Pezeshkpoor, K. Liphardt, S. LacroixDesmazes, J. Oldenburg, P. Broët have nothing to declare. At the time of writing J. Davidson was employed by and held stocks/shares in GlaxoSmithKline. A.Hincelin-Mery is employed by Sanofi. P. D¨onnes is an employee of SciCross AB. Dr. K¨onigs reports grants and personal fees from Bayer Vital GmbH for research support and speakers bureau, grants and personal fees from Biotest AG for research support and speakers bureau, grants and personal fees from CSL Behring for research support and speakers bureau, personal fees from Grifols for speakers bureau, grants from Intersero for reasearch support, grants and personal fees from Pfizer for research support and speakers bureau, grants and personal fees from Shire for research support and speakers bureau, grants and personal fees from Sobi for research support and speakers bureau, personal fees from Roche for expert testimony, outside the submitted work. The research leading to these results has received support from the Innovative Medicines Initiative Joint Undertaking under grant agreement no [115303], resources of which are composed of financial contribution from the European Union’s Seventh Framework Programme (FP7/2007-2013)and EFPIA companies. J.E. Davidson, A. Hincelin-Mery: belong to EFPIA (European Federation of Pharmaceutical Industries and Association) member companies in the IMI JU and costs related to their part in the research were carried by the respective companies as in kind contributions under the IMI JU scheme. This does not alter his adherence to PLOS ONE policies on sharing data and materials. All the company-employed authors declare that this does not alter their adherence to PLOS ONE policies on sharing data and materials.