About the Authors

Stéphane Pillet

Roles Formal analysis, Investigation, Methodology, Writing – original draft

Affiliations Medicago Inc., Québec City, Québec, Canada, Research Institute, McGill University Health Centre, Montreal, Québec, Canada

Julie Couillard

Roles Data curation, Formal analysis, Writing – original draft

Affiliation Medicago Inc., Québec City, Québec, Canada

Sonia Trépanier

Roles Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Medicago Inc., Québec City, Québec, Canada

Jean-François Poulin

Roles Data curation, Formal analysis, Validation

Affiliation Caprion Biosciences Inc., Montréal, Québec, Canada

Bader Yassine-Diab

Roles Data curation, Formal analysis, Validation

Affiliation Caprion Biosciences Inc., Montréal, Québec, Canada

Bruno Guy

Roles Investigation, Writing – original draft

Affiliation Expert/Consultant–Microbiology and Vaccinology, Lyon, France

Brian J. Ward

Roles Conceptualization, Investigation, Project administration, Writing – review & editing

Affiliations Medicago Inc., Québec City, Québec, Canada, Research Institute, McGill University Health Centre, Montreal, Québec, Canada

Nathalie Landry

Roles Conceptualization, Investigation, Supervision, Writing – review & editing

landryn@medicago.com

Affiliation Medicago Inc., Québec City, Québec, Canada

Competing Interests

BJW, NL, JC, and SP are paid employees of Medicago, and JFP and BYP are paid employees of Caprion Biosciences. Additionally, BJW has been a principal investigator of vaccine trials for several manufacturers, including Medicago Inc., for which his institution obtained research contracts. BJW has also received honoraria from several vaccine manufacturers for participation on Scientific Advisory Boards, including Medicago Inc. The Medicago’s VLP vaccine candidate is a product protected by patents owned by the company Medicago and the manuscript reports clinical results obtained with the candidate vaccine during a clinical trial authorized by United States of America and Canadian regulatory authorities. There are no other patents, products in development or marketed products associated with this research to declare. This does not alter our adherence to PLOS ONE policies on sharing data and materials.