PCR with electrospray ionization-mass spectrometry on bronchoalveolar lavage for detection of invasive mold infections in hematological patients

Anders Krifors; Volkan Özenci; Måns Ullberg; Malin Ackefors; Martin Jädersten; Kristoffer Strålin; Ola Blennow

doi:10.1371/journal.pone.0212812

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Open Access

Peer-reviewed

Research Article

PCR with electrospray ionization-mass spectrometry on bronchoalveolar lavage for detection of invasive mold infections in hematological patients

Anders Krifors ,

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Data curation, Investigation, Writing – original draft, Writing – review & editing

* E-mail: anders.krifors@regionvastmanland.se

Affiliation Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden

http://orcid.org/0000-0003-1230-0492

⨯
Volkan Özenci ,

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Formal analysis, Methodology, Supervision, Visualization, Writing – review & editing

Affiliations Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden, Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
⨯
Måns Ullberg ,

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Methodology, Supervision, Visualization, Writing – review & editing

Affiliations Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden, Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
⨯
Malin Ackefors ,

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Department of Infectious Diseases, Karolinska University Hospital, Huddinge, Sweden
⨯
Martin Jädersten ,

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Centre for Haematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden
⨯
Kristoffer Strålin ,

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Data curation, Methodology, Writing – review & editing

Affiliations Department of Infectious Diseases, Karolinska University Hospital, Huddinge, Sweden, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden
⨯
Ola Blennow

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Infectious Diseases, Karolinska University Hospital, Huddinge, Sweden, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden
⨯

PCR with electrospray ionization-mass spectrometry on bronchoalveolar lavage for detection of invasive mold infections in hematological patients

Anders Krifors,
Volkan Özenci,
Måns Ullberg,
Malin Ackefors,
Martin Jädersten,
Kristoffer Strålin,
Ola Blennow

Published: February 22, 2019
https://doi.org/10.1371/journal.pone.0212812

About the Authors

Anders Krifors

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Data curation, Investigation, Writing – original draft, Writing – review & editing

* E-mail: anders.krifors@regionvastmanland.se

Affiliation Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden

http://orcid.org/0000-0003-1230-0492

Volkan Özenci

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Formal analysis, Methodology, Supervision, Visualization, Writing – review & editing

Affiliations Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden, Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden

Måns Ullberg

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Methodology, Supervision, Visualization, Writing – review & editing

Malin Ackefors

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Department of Infectious Diseases, Karolinska University Hospital, Huddinge, Sweden

Martin Jädersten

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Centre for Haematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden

Kristoffer Strålin

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Data curation, Methodology, Writing – review & editing

Affiliations Department of Infectious Diseases, Karolinska University Hospital, Huddinge, Sweden, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden

Ola Blennow

Contributed equally to this work with: Anders Krifors, Volkan Özenci, Måns Ullberg, Malin Ackefors, Martin Jädersten, Kristoffer Strålin, Ola Blennow

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Infectious Diseases, Karolinska University Hospital, Huddinge, Sweden, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden

Competing Interests

The authors have declared that no competing interests exist.

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Fungal molds
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Aspergillus
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Polymerase chain reaction
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Diagnostic medicine
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Hematology
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Antifungals
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Aspergillus fumigatus
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Aspergillosis
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