About the Authors

Eugene Gonzalez-Lopez

Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Supervision, Validation, Visualization, Writing – original draft

Affiliation Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America

Yuka Kawasawa-Imamura

Roles Data curation, Formal analysis, Methodology, Software, Validation

Affiliations Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America, Genome Sciences Core Facility, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, Pennsylvania

Lijun Zhang

Roles Formal analysis, Validation, Writing – review & editing

Affiliations Genome Sciences Core Facility, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania

Xuemei Huang

Roles Formal analysis, Funding acquisition, Resources, Writing – review & editing

Affiliations Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America, Department of Neurology, Pennsylvania State University College of Medicine, Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States of America, Departments of Neurology, Neurosurgery and Radiology, Milton S. Hershey Medical Center, and Kinesiology, Pennsylvania State University, Hershey, Pennsylvania, United States of America

Walter A. Koltun

Roles Funding acquisition, Resources

Affiliation Department of Surgery, Division of Colon and Rectal Surgery, Pennsylvania State University, Hershey, Pennsylvania, United States of America

Matthew D. Coates

Contributed equally to this work with: Matthew D. Coates, Kent E. Vrana

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

kvrana@pennstatehealth.psu.edu (KV); mcoates@pennstatehealth.psu.edu (MC)

Affiliation Department of Medicine, Division of Gastroenterology & Hepatology, Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States of America

Kent E. Vrana

Contributed equally to this work with: Matthew D. Coates, Kent E. Vrana

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

kvrana@pennstatehealth.psu.edu (KV); mcoates@pennstatehealth.psu.edu (MC)

Affiliation Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.