Low mucosal-associated invariant T-cell number in peripheral blood of patients with immune thrombocytopenia and their response to prednisolone

Takaaki Maekawa; Yukiko Osawa; Yosuke Okada; Noriaki Tachi; Masahiro Teramoto; Toshikuni Kawamura; Toshikatsu Horiuchi; Shoichiro Kato; Ayako Kobayashi; Shinichi Kobayashi; Ken Sato; Fumihiko Kimura

doi:10.1371/journal.pone.0207149

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Open Access

Peer-reviewed

Research Article

Low mucosal-associated invariant T-cell number in peripheral blood of patients with immune thrombocytopenia and their response to prednisolone

Takaaki Maekawa ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft

* E-mail: doc00064@ndmc.ac.jp

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

http://orcid.org/0000-0002-8611-0862

⨯
Yukiko Osawa,

Roles Investigation

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
⨯
Yosuke Okada,

Roles Resources

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
⨯
Noriaki Tachi,

Roles Resources

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
⨯
Masahiro Teramoto,

Roles Resources

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
⨯
Toshikuni Kawamura,

Roles Investigation

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
⨯
Toshikatsu Horiuchi,

Roles Resources

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
⨯
Shoichiro Kato,

Roles Investigation

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
⨯
Ayako Kobayashi,

Roles Supervision

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
⨯
Shinichi Kobayashi,

Roles Supervision

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

http://orcid.org/0000-0002-1321-3908

⨯
Ken Sato,

Roles Supervision

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
⨯
Fumihiko Kimura

Roles Project administration, Supervision

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
⨯

Low mucosal-associated invariant T-cell number in peripheral blood of patients with immune thrombocytopenia and their response to prednisolone

Takaaki Maekawa,
Yukiko Osawa,
Yosuke Okada,
Noriaki Tachi,
Masahiro Teramoto,
Toshikuni Kawamura,
Toshikatsu Horiuchi,
Shoichiro Kato,
Ayako Kobayashi,
Shinichi Kobayashi

Published: November 8, 2018
https://doi.org/10.1371/journal.pone.0207149

About the Authors

Takaaki Maekawa

Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft

* E-mail: doc00064@ndmc.ac.jp

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

http://orcid.org/0000-0002-8611-0862

Yukiko Osawa

Roles Investigation

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

Yosuke Okada

Roles Resources

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

Noriaki Tachi

Roles Resources

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

Masahiro Teramoto

Roles Resources

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

Toshikuni Kawamura

Roles Investigation

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

Toshikatsu Horiuchi

Roles Resources

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

Shoichiro Kato

Roles Investigation

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

Ayako Kobayashi

Roles Supervision

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

Shinichi Kobayashi

Roles Supervision

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

http://orcid.org/0000-0002-1321-3908

Ken Sato

Roles Supervision

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

Fumihiko Kimura

Roles Project administration, Supervision

Affiliation Division of Hematology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan

Competing Interests

The authors have declared that no competing interests exist.

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Idiopathic thrombocytopenic purpura
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T cells
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Cytokines
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Corticosteroid therapy
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Blood
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Platelets
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Cytokine therapy
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