About the Authors

Masanosuke Ishigami

Roles Data curation, Formal analysis, Investigation, Writing – original draft

Affiliations Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital, Kobe, Japan

Hidetoshi Masumoto

Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Validation, Writing – original draft, Writing – review & editing

masumoto@kuhp.kyoto-u.ac.jp (HM); juny@cira.kyoto-u.ac.jp (JKY)

Affiliations Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

Takeshi Ikuno

Roles Investigation, Validation

Current address: Department of Cardiovascular Surgery, Takamatsu Red Cross Hospital, Takamatsu, Japan

Affiliations Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

Takayuki Aoki

Roles Investigation, Validation

Affiliation Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Masahide Kawatou

Roles Investigation, Methodology, Validation

Affiliations Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

Kenji Minakata

Roles Formal analysis, Methodology, Supervision

Current address: Division of Cardiovascular Surgery, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, United States of America

Affiliation Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Tadashi Ikeda

Roles Formal analysis, Supervision

Affiliation Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Ryuzo Sakata

Roles Supervision, Validation

Current address: Department of Cardiovascular Surgery, Osaka Red Cross Hospital, Osaka, Japan

Affiliation Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Jun K. Yamashita

Roles Conceptualization, Resources, Supervision, Validation, Writing – review & editing

masumoto@kuhp.kyoto-u.ac.jp (HM); juny@cira.kyoto-u.ac.jp (JKY)

Affiliation Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

Kenji Minatoya

Roles Conceptualization, Supervision, Validation

Affiliation Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Competing Interests

Competing interests is as follows: J. K. Yamashita is a founder, equity holder, and scientific adviser of iHeart Japan Corporation. J. K. Yamashita and H. Masumoto are co-inventors on multiple pluripotent stem cell-related patents. 1. Patent name: Method for producing mixed cell population of cardiomyocytes and vascular cells from induced pluripotent stem cell. Patent number: 9764063. Date of patent: September 19th, 2017. 2. Patent name: Method for producing myocardial sheet from embryonic stem cell. Patent number: 9623052. Date of patent: April 18th, 2017. This does not alter our adherence to PLOS ONE policies on sharing data and materials.