Inhibitors of lysosomal function or serum starvation in control or LAMP2 deficient cells do not modify the cellular levels of Parkinson disease-associated DJ-1/PARK 7 protein

Raúl Sánchez-Lanzas; José G. Castaño

doi:10.1371/journal.pone.0201152

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Peer-reviewed

Research Article

Inhibitors of lysosomal function or serum starvation in control or LAMP2 deficient cells do not modify the cellular levels of Parkinson disease-associated DJ-1/PARK 7 protein

Raúl Sánchez-Lanzas,

Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

Affiliations Departamento de Bioquímica, Instituto de Investigaciones Biomédicas “Alberto Sols”, UAM-CSIC, Facultad de Medicina UAM, Madrid, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Facultad de Medicina UAM, Madrid, Spain
⨯
José G. Castaño

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: joseg.castano@uam.es

Affiliations Departamento de Bioquímica, Instituto de Investigaciones Biomédicas “Alberto Sols”, UAM-CSIC, Facultad de Medicina UAM, Madrid, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Facultad de Medicina UAM, Madrid, Spain

http://orcid.org/0000-0002-6579-8442

⨯

Inhibitors of lysosomal function or serum starvation in control or LAMP2 deficient cells do not modify the cellular levels of Parkinson disease-associated DJ-1/PARK 7 protein

Raúl Sánchez-Lanzas,
José G. Castaño

Published: July 26, 2018
https://doi.org/10.1371/journal.pone.0201152

About the Authors

Raúl Sánchez-Lanzas

Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

Affiliations Departamento de Bioquímica, Instituto de Investigaciones Biomédicas “Alberto Sols”, UAM-CSIC, Facultad de Medicina UAM, Madrid, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Facultad de Medicina UAM, Madrid, Spain

José G. Castaño

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: joseg.castano@uam.es

http://orcid.org/0000-0002-6579-8442

Competing Interests

The authors have declared that no competing interests exist.

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Lysosomes
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Immunoblotting
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Serum proteins
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Gene expression
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Protein expression
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Protein synthesis
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Adenine
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Autophagic cell death
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