About the Authors

Samantha Yuille

Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

Affiliation 4DPharma Research Ltd., Aberdeen, United Kingdom

Nicole Reichardt

Roles Data curation, Formal analysis, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliation 4DPharma Research Ltd., Aberdeen, United Kingdom

Suchita Panda

Roles Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

Affiliation 4DPharma Research Ltd., Aberdeen, United Kingdom

Hayley Dunbar

Roles Investigation, Validation

Affiliation 4DPharma Research Ltd., Aberdeen, United Kingdom

Imke E. Mulder

Roles Conceptualization, Project administration, Supervision, Writing – review & editing

imke.mulder@4dpharmaplc.com

Affiliation 4DPharma Research Ltd., Aberdeen, United Kingdom

Competing Interests

The authors would like to declare the following competing interests: SY, NR, HD, SP, IEM are affiliated with and received funding for this study from 4D Pharma Research Ltd. The strains reported herein as being of therapeutic potential and their use in therapy are the subject of pending International Patent Application No. PCT/EP2018/065858, European Patent Application Nos. 18178136.0, 18179641.8, 18179634.3 and 18171893.3 and UK Patent Application No. 1810386.1, all of which are currently unpublished. The simulated microbiome system is the subject of pending European Patent Application No. 18170880.1, which is currently unpublished. This does not alter our adherence to PLOS ONE policies on sharing data and materials.