Machine learning-based identification of genetic interactions from heterogeneous gene expression profiles

Chihyun Park; JungRim Kim; Jeongwoo Kim; Sanghyun Park

doi:10.1371/journal.pone.0201056

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Open Access

Peer-reviewed

Research Article

Machine learning-based identification of genetic interactions from heterogeneous gene expression profiles

Chihyun Park,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Dept. of Computer Science, Yonsei University, Seodaemun-gu, Seoul, Korea

http://orcid.org/0000-0003-4995-2312

⨯
JungRim Kim,

Roles Formal analysis, Validation, Writing – review & editing

Affiliation Dept. of Computer Science, Yonsei University, Seodaemun-gu, Seoul, Korea
⨯
Jeongwoo Kim,

Roles Formal analysis, Validation, Writing – review & editing

Affiliation Dept. of Computer Science, Yonsei University, Seodaemun-gu, Seoul, Korea
⨯
Sanghyun Park

Roles Funding acquisition, Project administration, Writing – review & editing

* E-mail: sanghyun@yonsei.ac.kr

Affiliation Dept. of Computer Science, Yonsei University, Seodaemun-gu, Seoul, Korea

http://orcid.org/0000-0002-5196-6193

⨯

Machine learning-based identification of genetic interactions from heterogeneous gene expression profiles

Chihyun Park,
JungRim Kim,
Jeongwoo Kim,
Sanghyun Park

Published: July 26, 2018
https://doi.org/10.1371/journal.pone.0201056

About the Authors

Chihyun Park

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Dept. of Computer Science, Yonsei University, Seodaemun-gu, Seoul, Korea

http://orcid.org/0000-0003-4995-2312

JungRim Kim

Roles Formal analysis, Validation, Writing – review & editing

Affiliation Dept. of Computer Science, Yonsei University, Seodaemun-gu, Seoul, Korea

Jeongwoo Kim

Roles Formal analysis, Validation, Writing – review & editing

Affiliation Dept. of Computer Science, Yonsei University, Seodaemun-gu, Seoul, Korea

Sanghyun Park

Roles Funding acquisition, Project administration, Writing – review & editing

* E-mail: sanghyun@yonsei.ac.kr

Affiliation Dept. of Computer Science, Yonsei University, Seodaemun-gu, Seoul, Korea

http://orcid.org/0000-0002-5196-6193

Competing Interests

The authors have declared that no competing interests exist.

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Gene expression
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Machine learning
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Alzheimer's disease
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Interaction networks
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Machine learning algorithms
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Decision tree learning
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Genetic networks
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Gene regulatory networks
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