About the Authors

Annarosaria De Vito

Roles Formal analysis, Investigation

Affiliation Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy

Massimo Lazzaro

Roles Formal analysis, Investigation

Affiliation Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy

Ilaria Palmisano

Roles Formal analysis, Investigation

Current address: Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom.

Affiliation Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy

Davide Cittaro

Roles Formal analysis

Affiliation Center for Translational Genomics and Bioinformatics, IRCCS San Raffaele Scientific Institute, Milan, Italy

Michela Riba

Roles Formal analysis

Affiliation Center for Translational Genomics and Bioinformatics, IRCCS San Raffaele Scientific Institute, Milan, Italy

Dejan Lazarevic

Roles Investigation

Affiliation Center for Translational Genomics and Bioinformatics, IRCCS San Raffaele Scientific Institute, Milan, Italy

Makoto Bannai

Roles Conceptualization, Resources

Affiliation Frontier Research Labs, Institute for Innovation, Ajinomoto Co., Kawasaki, Tokyo, Japan

Davide Gabellini

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy

Maria Vittoria Schiaffino

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

schiaffino.mariavittoria@hsr.it

Affiliation Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy

Competing Interests

This study was funded by Ajinomoto Co., Inc., Japan and one of the authors [M.B.] is an employee of this commercial funder. No other employment or consultancy relationships exist with the commercial funder, and no patents, products in development, or marketed products result from this study. The authors declare that no competing interests exist and that the commercial affiliation of one of the authors does not alter the adherence of authors to all PLOS ONE policies on sharing data and materials.