Differential effects of TNF-α and IL-1β on the control of metal metabolism and cadmium-induced cell death in chronic inflammation

Paola Bonaventura; Aline Lamboux; Francis Albarède; Pierre Miossec

doi:10.1371/journal.pone.0196285

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Open Access

Peer-reviewed

Research Article

Differential effects of TNF-α and IL-1β on the control of metal metabolism and cadmium-induced cell death in chronic inflammation

Paola Bonaventura,

Roles Conceptualization, Data curation, Formal analysis, Writing – original draft

Affiliation Department of Immunology and Rheumatology, Immunogenomics and Inflammation Research Unit EA 4130, University of Lyon, Edouard Herriot Hospital, Lyon, France
⨯
Aline Lamboux,

Roles Data curation, Investigation

Affiliation Geology Laboratory–Department of Earth Sciences, Ecole Normale Supérieure de Lyon and CNRS Lyon, France
⨯
Francis Albarède,

Roles Conceptualization, Supervision

Affiliation Geology Laboratory–Department of Earth Sciences, Ecole Normale Supérieure de Lyon and CNRS Lyon, France
⨯
Pierre Miossec

Roles Conceptualization, Supervision, Writing – review & editing

* E-mail: pierre.miossec@univ-lyon1.fr

Affiliation Department of Immunology and Rheumatology, Immunogenomics and Inflammation Research Unit EA 4130, University of Lyon, Edouard Herriot Hospital, Lyon, France

http://orcid.org/0000-0002-3280-6346

⨯

Differential effects of TNF-α and IL-1β on the control of metal metabolism and cadmium-induced cell death in chronic inflammation

Paola Bonaventura,
Aline Lamboux,
Francis Albarède,
Pierre Miossec

Published: May 16, 2018
https://doi.org/10.1371/journal.pone.0196285

About the Authors

Paola Bonaventura

Roles Conceptualization, Data curation, Formal analysis, Writing – original draft

Affiliation Department of Immunology and Rheumatology, Immunogenomics and Inflammation Research Unit EA 4130, University of Lyon, Edouard Herriot Hospital, Lyon, France

Aline Lamboux

Roles Data curation, Investigation

Affiliation Geology Laboratory–Department of Earth Sciences, Ecole Normale Supérieure de Lyon and CNRS Lyon, France

Francis Albarède

Roles Conceptualization, Supervision

Affiliation Geology Laboratory–Department of Earth Sciences, Ecole Normale Supérieure de Lyon and CNRS Lyon, France

Pierre Miossec

Roles Conceptualization, Supervision, Writing – review & editing

* E-mail: pierre.miossec@univ-lyon1.fr

Affiliation Department of Immunology and Rheumatology, Immunogenomics and Inflammation Research Unit EA 4130, University of Lyon, Edouard Herriot Hospital, Lyon, France

http://orcid.org/0000-0002-3280-6346

Competing Interests

The authors have declared that no competing interests exist.

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Cytokines
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Inflammation
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Apoptosis
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Monocytes
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Gene expression
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Rheumatoid arthritis
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Homeostasis
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Zinc
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