A-674563, a putative AKT1 inhibitor that also suppresses CDK2 activity, inhibits human NSCLC cell growth more effectively than the pan-AKT inhibitor, MK-2206

Open Access

Peer-reviewed

Research Article

About the Authors

Paige M. Chorner

Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada

Roger A. Moorehead

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – review & editing

Affiliation Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada

The authors have declared that no competing interests exist.

Non-small cell lung cancer
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Cancer treatment
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Cell proliferation
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Lung and intrathoracic tumors
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Cell cycle and cell division
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Protein expression
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Synthesis phase
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Cell cycle inhibitors
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