About the Authors

Chie Owa

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

Affiliation Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, United States of America

Matthew Poulin

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

Affiliation EpigenDx, Inc., Hopkinton, MA, United States of America

Liying Yan

Roles Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

Affiliation EpigenDx, Inc., Hopkinton, MA, United States of America

Toshi Shioda

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

tshioda@mgh.harvard.edu

Affiliations Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, United States of America, Harvard Medical School, Boston, MA, United States of America

Competing Interests

The commercial affiliation of MP and LY with EpigenDx does not alter our adherence to PLOS ONE policies on sharing data and materials.