Mouse IgG2c Fc loop residues promote greater receptor-binding affinity than mouse IgG2b or human IgG1

Open Access

Peer-reviewed

Research Article

About the Authors

Daniel J. Falconer

Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

Affiliation Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology Iowa State University, Ames, IA, United States of America

Adam W. Barb

Roles Conceptualization, Investigation, Supervision, Writing – original draft, Writing – review & editing

Affiliation Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology Iowa State University, Ames, IA, United States of America

The authors have declared that no competing interests exist.

Mice
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Crystals
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NMR spectroscopy
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Crystallization
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Sodium chloride
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Crystal structure
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Immune system
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Protein structure
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