The peroxisome proliferator-activated receptor agonist pioglitazone and 5-lipoxygenase inhibitor zileuton have no effect on lung inflammation in healthy volunteers by positron emission tomography in a single-blind placebo-controlled cohort study

• Delphine L. Chen ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: chend@wustl.edu

  Affiliations Mallinckrodt Institute of Radiology, Division of Radiological Sciences, Washington University School of Medicine, St. Louis, MO, United States of America, Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO, United States of America

  http://orcid.org/0000-0002-0150-5401

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• Howard J. Huang,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center at Dallas, Dallas, TX, United States of America

  ⨯
• Derek E. Byers,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• Adrian Shifren,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• Bryan Belikoff,

  Roles Methodology, Visualization, Writing – review & editing

  Affiliation Mallinckrodt Institute of Radiology, Division of Radiological Sciences, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• Jacquelyn T. Engle,

  Roles Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Mallinckrodt Institute of Radiology, Division of Radiological Sciences, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• Elizabeth Arentson,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Mallinckrodt Institute of Radiology, Division of Radiological Sciences, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• Debra Kemp,

  Roles Data curation, Investigation, Project administration

  Affiliation Center for Clinical Studies, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• Sharon Phillips,

  Roles Data curation, Investigation, Project administration, Writing – review & editing

  Affiliation Mallinckrodt Institute of Radiology, Division of Radiological Sciences, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• David E. Scherrer,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• Hideji Fujiwara,

  Roles Data curation, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• Katherine J. Spayd,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Mallinckrodt Institute of Radiology, Division of Radiological Sciences, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• Frank J. Brooks,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Mallinckrodt Institute of Radiology, Division of Radiological Sciences, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• Richard A. Pierce,

  Roles Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
• Mario Castro,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO, United States of America

  ⨯
•  [ ... ],
• Warren Isakow

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO, United States of America

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