About the Authors

Roland Züst

Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Current address: Spiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland

Affiliation Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore

Shi-Hua Li

Roles Formal analysis, Investigation, Methodology

Affiliations Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

Xuping Xie

Roles Formal analysis, Investigation, Methodology

Affiliations Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore, Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, United States of America

Sumathy Velumani

Roles Formal analysis, Investigation, Methodology

Affiliation Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore

Melissa Chng

Roles Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore

Ying-Xiu Toh

Roles Investigation, Methodology

Affiliation Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore

Jing Zou

Roles Investigation, Methodology

Affiliations Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore, Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, United States of America

Hongping Dong

Roles Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore

Chao Shan

Roles Formal analysis, Investigation, Methodology

Affiliations Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore, Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, United States of America

Jassia Pang

Roles Data curation, Investigation, Methodology, Project administration, Writing – original draft

Affiliation Biological Resource Centre, Agency for Science, Technology and Research, Singapore, Singapore

Cheng-Feng Qin

Roles Resources, Supervision

Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

Evan W. Newell

Roles Conceptualization, Resources, Supervision

Affiliation Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore

Pei-Yong Shi

Roles Conceptualization, Data curation, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

Katja_Fink@immunol.a-star.edu.sg (KF); peshi@utmb.edu (PYS)

Affiliations Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore, Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, United States of America, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX, United States of America, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, United States of America

Katja Fink

Roles Conceptualization, Data curation, Formal analysis, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

Katja_Fink@immunol.a-star.edu.sg (KF); peshi@utmb.edu (PYS)

Affiliation Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: KF, CFQ and PYS are inventors of a patent for the use of DENV 2-O-MTase mutants as vaccine. KF is a recipient of a research grant from Merck Singapore. This does not alter our adherence to PLOS ONE policies on sharing data and materials.