About the Authors
- Kristine Lillebø Holm
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Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft
Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
- Randi Gussgard Syljuåsen
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Roles Conceptualization, Data curation, Resources, Writing – review & editing
Affiliation Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway
- Grete Hasvold
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Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway
- Lene Alsøe
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Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway
- Hilde Nilsen
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Roles Conceptualization, Resources, Writing – review & editing
Affiliation Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway
- Kristina Ivanauskiene
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Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
- Philippe Collas
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Roles Conceptualization, Resources, Writing – review & editing
Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
- Sergey Shaposhnikov
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Roles Data curation, Investigation, Resources, Writing – review & editing
Affiliations Comet Biotech AS, Norgenotech AS, Oslo, Norway, Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
- Andrew Collins
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Roles Conceptualization, Resources, Writing – review & editing
Affiliations Comet Biotech AS, Norgenotech AS, Oslo, Norway, Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
- Randi Larsen Indrevær
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Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
- Pål Aukrust
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Roles Conceptualization, Resources, Writing – review & editing
Affiliations Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway
- Børre Fevang
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Roles Conceptualization, Resources, Supervision, Writing – review & editing
Affiliations Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway
- Heidi Kiil Blomhoff
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Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft
* E-mail: h.k.blomhoff@medisin.uio.no
Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
Competing Interests
HKB is a share-holder of AS Vitas. AS Vitas has no part or role in this study. We confirm that this commercial affiliation does not alter our adherence to PLOS ONE policies on sharing data and materials. SS and AC have shares in Norgenotech AS (Comet Biotech AS is a daughter company). These companies are engaged in research activities and have been involved in various EC and national studies, including Norwegian SkatteFunn tax deduction scheme awarded to R&D carrying SMEs. Their financial involvement in research is limited by covering salaries and materials for their employees. These companies have never been acting as funders and have no commercial interest in outcomes of the research projects they participate in. In this particular study AC and SS have been involved in all of the aspects connected with carrying out the comet assay on the samples of cells, which included the design of the comet assay experiments (including x-irradiation doses and conditions), carrying out the experimental part, data collection and analysis, general scientific discussions and manuscript preparation. Norgenotech & Comet Biotech financial involvement in the study: salary for SS and coverage of the reagents, materials, lab rent and technical assistance connected with carrying out the experiments (these actual costs of Norgenotech were covered by the University of Oslo with no commercial profit or overheads). Thus both AC and SS have no commercial or financial interests in the study outcomes, and their affiliated companies have not acted as funders in the study. Finally, we confirm that this commercial affiliation does not alter our adherence to PLOS ONE policies on sharing data and materials.