About the Authors

Fumihiko Takeuchi

Roles Formal analysis, Writing – original draft, Writing – review & editing

fumihiko@takeuchi.name (FT); nokato@ri.ncgm.go.jp (NK)

Affiliation Department of Gene Diagnostics and Therapeutics, National Center for Global Health and Medicine, Tokyo, Japan

Tomohiro Katsuya

Roles Resources, Writing – review & editing

Affiliation Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan

Ryosuke Kimura

Roles Resources, Writing – review & editing

Affiliation Department of Human Biology and Anatomy, Graduate School of Medicine, University of the Ryukyus, Nishihara-cho, Japan

Toru Nabika

Roles Resources, Writing – review & editing

Affiliation Department of Functional Pathology, Shimane University School of Medicine, Izumo, Japan

Minoru Isomura

Roles Resources, Writing – review & editing

Affiliation Department of Functional Pathology, Shimane University School of Medicine, Izumo, Japan

Takayoshi Ohkubo

Roles Resources, Writing – review & editing

Affiliation Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan

Yasuharu Tabara

Roles Resources, Writing – review & editing

Affiliation Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan

Ken Yamamoto

Roles Resources, Writing – review & editing

Affiliation Department of Medical Chemistry, Kurume University School of Medicine, Kurume, Japan

Mitsuhiro Yokota

Roles Resources, Writing – review & editing

Affiliation Department of Genome Science, School of Dentistry, Aichi Gakuin University, Nagoya, Japan

Xuanyao Liu

Roles Formal analysis, Writing – review & editing

Affiliations Saw Swee Hock School of Public Health, National University of Singapore, Singapore, NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, Singapore

Woei-Yuh Saw

Roles Formal analysis, Writing – review & editing

Affiliations Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Life Sciences Institute, National University of Singapore, Singapore, Singapore

Dolikun Mamatyusupu

Roles Formal analysis, Writing – review & editing

Affiliation College of the Life Sciences and Technology, Xinjiang University, Urumqi, China

Wenjun Yang

Roles Formal analysis, Writing – review & editing

Affiliation Key Laboratory of Reproduction and Heredity of Ningxia Region, Ningxia Medical University, Yinchuan, Ningxia, China

Shuhua Xu

Roles Resources, Writing – review & editing

Affiliations Max Planck Independent Research Group on Population Genomics, Chinese Academy of Sciences and Max Planck Society Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Shanghai, China, School of Life Sciences and Technology, ShanghaiTech University, Shanghai, China, Collaborative Innovation Center of Genetics and Development, Shanghai, China

Japanese Genome Variation Consortium

Membership of the Japanese Genome Variation Consortium is provided in the Acknowledgments.

Yik-Ying Teo

Contributed equally to this work with: Yik-Ying Teo, Norihiro Kato

Roles Conceptualization, Resources, Writing – review & editing

Affiliations Department of Gene Diagnostics and Therapeutics, National Center for Global Health and Medicine, Tokyo, Japan, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, Singapore, Life Sciences Institute, National University of Singapore, Singapore, Singapore, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore, Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore

Norihiro Kato

Contributed equally to this work with: Yik-Ying Teo, Norihiro Kato

Roles Conceptualization, Resources, Writing – original draft, Writing – review & editing

fumihiko@takeuchi.name (FT); nokato@ri.ncgm.go.jp (NK)

Affiliation Department of Gene Diagnostics and Therapeutics, National Center for Global Health and Medicine, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.