About the Authors

Diego Alvarado

Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

dalvarado@celldex.com

Current address: Celldex Therapeutics Inc., New Haven, Connecticut, United States of America

Affiliation Kolltan Pharmaceuticals., New Haven, Connecticut, United States of America

Gwenda F. Ligon

Contributed equally to this work with: Gwenda F. Ligon, Jay S. Lillquist

Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

Current address: Celldex Therapeutics Inc., New Haven, Connecticut, United States of America

Affiliation Kolltan Pharmaceuticals., New Haven, Connecticut, United States of America

Jay S. Lillquist

Contributed equally to this work with: Gwenda F. Ligon, Jay S. Lillquist

Roles Formal analysis, Investigation, Methodology, Validation

Current address: Celldex Therapeutics Inc., New Haven, Connecticut, United States of America

Affiliation Kolltan Pharmaceuticals., New Haven, Connecticut, United States of America

Scott B. Seibel

Roles Formal analysis, Investigation, Methodology, Validation

Affiliation Kolltan Pharmaceuticals., New Haven, Connecticut, United States of America

Gerald Wallweber

Roles Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – review & editing

Affiliation Monogram Biosciences, Laboratory Corporation of America® Holdings, South San Francisco, California, United States of America

Veronique M. Neumeister

Roles Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization

Affiliation Yale Pathology Tissue Services, Yale University, New Haven, Connecticut, United States of America

David L. Rimm

Roles Methodology, Project administration, Resources, Software

Affiliation Yale Pathology Tissue Services, Yale University, New Haven, Connecticut, United States of America

Gerald McMahon

Roles Project administration, Supervision, Writing – review & editing

Current address: Harpoon Therapeutics, South San Francisco, California, United States of America.

Affiliation Kolltan Pharmaceuticals., New Haven, Connecticut, United States of America

Theresa M. LaVallee

Roles Conceptualization, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Current address: Celldex Therapeutics Inc., New Haven, Connecticut, United States of America

Affiliation Kolltan Pharmaceuticals., New Haven, Connecticut, United States of America

Competing Interests

DA, GFL, JSL, SBS AND TML are full time employees of Celldex Therapeutics (http://www.celldex.com/), which acquired Kolltan Pharmaceuticals in 2016. DA and TML are inventors in patent applications WO/2016/168634A1 and WO/2016/040622A1. The anti-ErbB3 mAb KTN3379 (now CDX-3379) is in clinical development at the time of this submission. GW is a full time employee of Monogram Biosciences. This does not alter our adherence to PLOS ONE policies on sharing data and materials.