About the Authors

Lauren G. Holinka

Contributed equally to this work with: Lauren G. Holinka, Vivian O’Donnell

Affiliation Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York, United States of America

Vivian O’Donnell

Contributed equally to this work with: Lauren G. Holinka, Vivian O’Donnell

Affiliations Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York, United States of America, Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut, United States of America

Guillermo R. Risatti

Affiliation Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut, United States of America

Paul Azzinaro

Affiliations Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York, United States of America, Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America

Jonathan Arzt

Affiliation Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York, United States of America

Carolina Stenfeldt

Affiliation Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York, United States of America

Lauro Velazquez-Salinas

Affiliations Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York, United States of America, Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America

Jolene Carlson

Affiliations Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York, United States of America, Biosecurity Research Institute and Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, United States of America

Douglas P. Gladue

Affiliation Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York, United States of America

Manuel V. Borca

manuel.borca@ars.usda.gov

Affiliation Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, New York, United States of America

Competing Interests

We do declare competing interests with a patent "Development of a novel live attenuated classical swine fever based in the genetic manipulation of a putative fusion peptide area in the virus structural Glycoprotein E2” Invention Report Docket No 104.15 7/22/2015. However, this patent does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: MB DG. Funding acquisition: MB. Investigation: LH VO GR PA JA CS LV JC DG MB. Methodology: VO LV GR. Project administration: MB. Resources: MB. Validation: LH VO GR PA JA CS LV JC DG. Visualization: MB GR VO LV. Writing – original draft: MB LH. Writing – review & editing: LH VO GR PA JA CS LV JC DG.