About the Authors

Denis Collins

denis.collins@dcu.ie (DC); martin.weisser@roche.com (MW)

Affiliation National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland

Wolfgang Jacob

Affiliation Roche Innovation Center Munich, Penzberg, Germany

Juan Miguel Cejalvo

Affiliation Department of Medical Oncology, Institute of Health Research INCLIVA, University of Valencia, Valencia, Spain

Maurizio Ceppi

Affiliation Roche Innovation Center Munich, Penzberg, Germany

Ian James

Affiliation A4P Consulting Ltd, Sandwich, United Kingdom

Max Hasmann

Affiliation Roche Innovation Center Munich, Penzberg, Germany

John Crown

Affiliations National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland, Department of Medical Oncology, St. Vincent's University Hospital, Dublin, Ireland

Andrés Cervantes

Affiliation Department of Medical Oncology, Institute of Health Research INCLIVA, University of Valencia, Valencia, Spain

Martin Weisser

denis.collins@dcu.ie (DC); martin.weisser@roche.com (MW)

Affiliation Roche Innovation Center Munich, Penzberg, Germany

Birgit Bossenmaier

Affiliation Roche Innovation Center Munich, Penzberg, Germany

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: WJ, MC, MH, MW, BB are employees of Roche Penzberg, Germany and WJ, MH and MW have ownership of stocks or shares in Roche. DC has received research grants and travel grants and honoraria for speaking or participation at meetings from Roche. JC has received research grants from Roche. IJ is an employee of A4P Consulting Ltd. and was involved in the collection of biomarker data in the study; Roche Diagnostics funded this consultancy role. JMC and AC declare no conflicts of interest.

Author Contributions

Conceptualization: MC MH MW BB. Data curation: DC WJ JMC. Formal analysis: DC WJ JMC. Funding acquisition: MH. Investigation: DC JMC AC MW BB. Methodology: DC JMC. Project administration: MW. Resources: DC JMC MC IJ JC AC BB. Supervision: JC MW BB. Validation: DC JMC JC AC MW BB. Visualization: DC WJ BB. Writing – original draft: DC WJ BB. Writing – review & editing: DC WJ JMC MC IJ MH JC AC MW BB.