About the Authors

Takehiro Kamo

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Hiroshi Akazawa

akazawah-tky@umin.ac.jp (HA); komuro-tky@umin.ac.jp (IK)

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Wataru Suda

Affiliations Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan, Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan

Akiko Saga-Kamo

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Yu Shimizu

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Hiroki Yagi

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Qing Liu

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Seitaro Nomura

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Atsuhiko T. Naito

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Norifumi Takeda

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Mutsuo Harada

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Haruhiro Toko

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Hidetoshi Kumagai

Affiliations Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Department of Advanced Clinical Science and Therapeutics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Yuichi Ikeda

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Eiki Takimoto

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Jun-ichi Suzuki

Affiliation Department of Advanced Clinical Science and Therapeutics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Kenya Honda

Affiliations Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

Hidetoshi Morita

Affiliation Graduate School of Environmental and Life Science, Okayama University, Okayama, Japan

Masahira Hattori

Affiliations Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan

Issei Komuro

akazawah-tky@umin.ac.jp (HA); komuro-tky@umin.ac.jp (IK)

Affiliation Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Competing Interests

The study was supported in part by Takeda Pharmaceutical Co., Ltd., Daiichi Sankyo Co., Ltd., Shionogi & Co., Ltd., Nippon Boehringer Ingelheim Co., Ltd., Bristol-Myers Squibb K.K., MSD K.K., Sanofi K.K., and Sumitomo Dainippon Pharma Co., Ltd. There are no patents, products in development, or marketed products to declare.

Author Contributions

Conceptualization: HA IK. Data curation: WS M. Hattori. Formal analysis: SN ATN NT M. Harada HT HK YI ET JS. Funding acquisition: HA. Investigation: WS HM. Methodology: KH HM M.Hattori. Resources: TK ASK YS HY QL. Writing – original draft: TK. Writing – review & editing: HA IK.