Low magnitude high frequency vibration promotes adipogenic differentiation of bone marrow stem cells via P38 MAPK signal

Qian Zhao; Yuezhi Lu; Haiyang Yu; Xueqi Gan

doi:10.1371/journal.pone.0172954

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Open Access

Peer-reviewed

Research Article

Low magnitude high frequency vibration promotes adipogenic differentiation of bone marrow stem cells via P38 MAPK signal

Qian Zhao ,

Contributed equally to this work with: Qian Zhao, Yuezhi Lu

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Yuezhi Lu ,

Contributed equally to this work with: Qian Zhao, Yuezhi Lu

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Haiyang Yu ,

* E-mail: Yhyang6812@foxmail.com (HY); smiling99938@qq.com (XG)

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Xueqi Gan

* E-mail: Yhyang6812@foxmail.com (HY); smiling99938@qq.com (XG)

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯

Low magnitude high frequency vibration promotes adipogenic differentiation of bone marrow stem cells via P38 MAPK signal

Qian Zhao,
Yuezhi Lu,
Haiyang Yu,
Xueqi Gan

Published: March 2, 2017
https://doi.org/10.1371/journal.pone.0172954

About the Authors

Qian Zhao

Contributed equally to this work with: Qian Zhao, Yuezhi Lu

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China

Yuezhi Lu

Contributed equally to this work with: Qian Zhao, Yuezhi Lu

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China

Haiyang Yu

* E-mail: Yhyang6812@foxmail.com (HY); smiling99938@qq.com (XG)

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China

Xueqi Gan

* E-mail: Yhyang6812@foxmail.com (HY); smiling99938@qq.com (XG)

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: QZ YL HY XG. Data curation: QZ XG. Formal analysis: QZ XG. Funding acquisition: XG HY. Investigation: QZ. Methodology: QZ YL XG. Project administration: HY. Resources: QZ HY. Supervision: HY. Validation: QZ. Writing – original draft: QZ. Writing – review & editing: QZ XG HY.

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Vibration
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Protein kinase signaling cascade
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Oils
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Mesenchymal stem cells
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Gene expression
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MAPK signaling cascades
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Cell staining
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Adipocytes
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