About the Authors

Qingqing Liu

Affiliation Department of Pathology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

John Stewart

Affiliation Department of Pathology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Hua Wang

Affiliation Department of Gastrointestinal Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Asif Rashid

Affiliation Department of Pathology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Jun Zhao

Affiliation Department of Pathology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Matthew H. Katz

Affiliation Department of Surgical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Jeffrey E. Lee

Affiliation Department of Surgical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Jason B. Fleming

Affiliation Department of Surgical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Anirban Maitra

Affiliation Department of Pathology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Robert A. Wolff

Affiliation Department of Gastrointestinal Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Gauri R. Varadhachary

Affiliation Department of Gastrointestinal Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Sunil Krishnan

Affiliation Department of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Huamin Wang

hmwang@mdanderson.org

Affiliation Department of Pathology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Competing Interests

SK received funding from Polaris Pharmaceuticals, Inc. for preclinical studies with ADI-PEG20. However, this funding was not used in this study. There are no financial disclosures from the other authors.

Author Contributions

Conceptualization: SK JS QL HMW. Data curation: QL JS HMW. Formal analysis: QL HMW JZ JS. Funding acquisition: HMW SK. Investigation: QL JZ HW. Methodology: JS HW AR. Project administration: HMW. Resources: HW MHK JEL JBF AM RAW GV SK. Supervision: HMW. Validation: QL HMW JS. Visualization: QL HMW. Writing – original draft: QL. Writing – review & editing: QL JS HW MHK JBF JEL GV SK AR HMW.