About the Authors

Bryan Kaye

Contributed equally to this work with: Bryan Kaye, Peter J. Foster, Tae Yeon Yoo

bryankaye@fas.harvard.edu

Affiliations John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, United States of America, FAS Center for Systems Biology, Harvard University, Cambridge, MA, United States of America

Peter J. Foster

Contributed equally to this work with: Bryan Kaye, Peter J. Foster, Tae Yeon Yoo

Affiliations John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, United States of America, FAS Center for Systems Biology, Harvard University, Cambridge, MA, United States of America

Tae Yeon Yoo

Contributed equally to this work with: Bryan Kaye, Peter J. Foster, Tae Yeon Yoo

Affiliations John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, United States of America, FAS Center for Systems Biology, Harvard University, Cambridge, MA, United States of America

Daniel J. Needleman

Affiliations John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, United States of America, FAS Center for Systems Biology, Harvard University, Cambridge, MA, United States of America, Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, United States of America

Competing Interests

TYY was supported in part by the Samsung scholarship (https://www.ssscholarship.com/community/HomeEn.screen). This does not alter our adherence to PLOS ONE policies on sharing data and materials, and Samsung had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Author Contributions

Conceptualization: BK PJF TYY DJN. Data curation: BK TYY. Formal analysis: BK PJF TYY. Funding acquisition: DJN. Investigation: BK PJF TYY. Methodology: BK PJF TYY DJN. Project administration: DJN. Resources: BK PJF TYY. Software: BK PJF TYY. Supervision: DJN. Validation: BK PJF TYY. Visualization: BK PJF TYY. Writing – original draft: BK PJF TYY DJN. Writing – review & editing: BK PJF TYY DJN.