About the Authors
- Hui Chen Su
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Affiliation Department of Pharmacy, Chi-Mei Medical Center, Tainan, Taiwan
- Yan A. Liang
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Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America
- Ying-Jung J. Lai
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Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America
- Yi-Lin Chiu
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Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America
- Robert B. Barndt
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Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America
- Frank Shiao
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Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America
- Hsiang-Hua D. Chang
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Affiliations Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America, Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan
- Dajun D. Lu
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Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America
- Nanxi Huang
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Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America
- Chun-Che Tseng
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Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America
- Jehng-Kang Wang
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Affiliation Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan
- Ming-Shyue Lee
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Affiliation Graduate Institute of Biochemistry and Molecular Biology, College of Medicine National Taiwan University, Taipei, Taiwan
- Michael D. Johnson
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Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America
- Shih-Ming Huang
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* E-mail: lincy@georgetown.edu (CYL); shihming@mail.ndmctsgh.edu.tw (SMH)
Affiliation Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan
- Chen-Yong Lin
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* E-mail: lincy@georgetown.edu (CYL); shihming@mail.ndmctsgh.edu.tw (SMH)
Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America
Competing Interests
C.-Y.L is an inventor on US patents #6,077,938 (Title: Monoclonal antibody to an 80-kDa protease) and #6,677,377 (Title: Structure based discovery of inhibitors of matriptase for the cancer diagnosis and therapy by detection and inhibition of matriptase activity), and M.D.J and C.-Y.L are inventors on US patent #7,355,015 (Title: Matriptase, a serine protease and its applications). This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.
Author Contributions
Conceptualization: JKW MDJ CYL. Data curation: MDJ CYL. Formal analysis: MDJ CYL. Funding acquisition: HCS SMH. Investigation: YAL YJJL YLC RBB FS HHDC DDL NH CCT. Methodology: JKW MSL CYL. Project administration: MDJ. Resources: MDJ. Supervision: MDJ CYL. Visualization: YAL YJJL YLC RBB FS HHDC DDL NH CCT. Writing – original draft: CYL. Writing – review & editing: MDJ.