About the Authors

Leah R. Reznikov

Affiliations Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

David K. Meyerholz

Affiliation Department of Pathology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Ryan J. Adam

Affiliations Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, Iowa, United States of America

Mahmoud Abou Alaiwa

Affiliations Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Omar Jaffer

Affiliation Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Andrew S. Michalski

Affiliation Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Linda S. Powers

Affiliations Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Margaret P. Price

Affiliations Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

David A. Stoltz

Affiliations Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Department of Molecular Physiology and Biophysics, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, Iowa, United States of America

Michael J. Welsh

michael-welsh@uiowa.edu

Affiliations Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Department of Molecular Physiology and Biophysics, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Howard Hughes Medical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Competing Interests

The authors declare no competing interests.

Author Contributions

Conceptualization: LRR DAS DKM MAA OJ ASM MJW RJA. Data curation: LRR DKM RJA. Formal analysis: LRR DKM RJA. Funding acquisition: LRR DAS MJW. Investigation: LRR OJ MAA DKM RJA. Methodology: LSP MPP DKM ASM OJ MAA RJA. Project administration: LRR DKM MJW MPP DAS. Resources: LRR MPP DAS DKM MJW. Software: OJ ASM LRR RJA. Supervision: LRR DAS MJW DKM MPP. Validation: LRR ASM OJ MPP RJA LSP. Visualization: LRR DKM MAA RJA. Writing – original draft: LRR MJW. Writing – review & editing: LRR DAS DKM MAA LSP MPP ASM MJW RJA.